Level of Liver Enzymes in Patients with Mono-Parasitic Infections

Authors
M. Rahimi 1, 2
F. Kheiandish 3
Z. Arab-Mazar 4
A. Mirzapour 1
1 Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
2 Department of Parasitology and Mycology, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, IR Iran
3 Department of Parasitology and Mycology, School of Medicine, RaziHerbal Medicines Research Center, Lorestan, University of Medical Sciences, Khorramabad, IR Iran
4 Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Abstract
Background: Parasitic infections can cause different chemical changes in human body. This study was designed to determine the liver aminotransferase changes in Iranian people infected by parasite.
Materials and Methods: In this cross-sectional study, blood samples were collected from 183 parasite-infected patients. After serum isolation in laboratory, Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) rates of all samples were measured according to IFCC standard method, and after recording in the information form, the results were analyzed using descriptive statistics.
Results: The results of this study showed that patients were infected by 19 different types of parasites. Also, the results showed that the average value ​​of ALT and AST in patients were equal to 32.30 ±23.40 and 38.60±34.80, respectively. The ANOVA test showed remarkable statistical differences between these values ​​and various infections. There was positive and significant correlation between ALT and AST.
Conclusion: The abnormality in liver function in patients with eosinophilia can be caused by parasitic infections in endemic areas; therefore, it can be the cause of a differential diagnosis for physicians. Generally, non-significant changes in transaminase levels can also be attributed to the infection low intensity in patients tested.

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Infection Epidemiology and Microbiology
Volume 3, Issue 4 - Serial Number 9
December 2017
Pages 137-142