The Prevalence and Bacterial Etiology of Nosocomial Infections in Poursina Hospital of Rasht During 2013-2015

Document Type : Original Research

Authors
1 Razi Clinical Research Development Center, Guilan University of Medical Sciences, Rasht, Iran
2 Department of Internal Medicine, Guilan University of Medical Sciences, Rasht, Iran
3 Department of Health, Nutrition, and Infectious Diseases, Guilan University of Medical Sciences, Rasht, Iran
Abstract
Aims: The present study aimed to determine the prevalence of nosocomial infections and their bacterial agents in patients admitted to Poursina Medical and Educational Center of Rasht.

Materials & Methods: The present retrospective descriptive study was conducted by referring to the Infection Control Unit of Poursina hospital and investigating the records of patients with culture-positive nosocomial infections from April 2013 until the end of September 2015. Bacterial agents were diagnosed based on the standard microbiological tests.

Results: During the research period, urinary tract and blood infections were reported as the highest and lowest nosocomial infections, respectively. The most common strains causing nosocomial infections were Acinetobacter spp. (24.7%) (as the most common strain causing respiratory infection), Escherichia coli (22.9%) (as the most common strain causing urinary tract infection), and Enterobacter spp. (19.9%) (as the most common strain causing postoperative infection). Based on the frequency distribution of bacterial strains in hospital wards, Acinetobacter spp was reported as the most common strain isolated from patients in the intensive care unit.

Conclusion: According to the present study results, Acinetobacter spp was the most common strain isolated, and UTIs were the most common type of infection. Due to the prevalence of UTIs and the financial, physical, and social damage they impose to the whole country and the constant change of common pathogens and their susceptibility and antibiotic resistance patterns, it is necessary to conduct studies on this issue in the academic centers of each province at regular intervals.

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1. Falahi J, Khaledi A, Alikhani MY, Taghipour A, AMEL JS, Honarmand M, et al. Prevalence of Nosocomial Infection in DifferentWards of Ghaem Hospital, Mashhad. Avicenna J Clin Microbiol Infect. 2017;4(2
):40297.
2. A. MT. Nosocomial Infections: a Global Problem. Hakim Health Sys Res. 2016;19(2):100-2.
3. Kouchak F, Askarian M. Nosocomial infections: the definition criteria. Iran J Med Sci. 2012;37(2):72.
4. Mulu W, Kibru G, Beyene G, Damtie M. Postoperative Nosocomial Infections and Antimicrobial Resistance Pattern of Bacteria Isolates among Patients Admitted at Felege Hiwot Referral Hospital, Bahirdar, Ethiopia. Ethiop J Health Sci. 2012;22(1):7-18.
5. Hoseini MB, Abdinia B, Rezaee M, Oskouie S. The study of nosocomial infections in neonatal intensive care unit: A prospective study in northwest Iran. Int J Pediatr. 2014;2(3):25-33.
6. Pachori P, Gothalwal R, Gandhi P. Emergence of antibiotic resistance Pseudomonas aeruginosa in intensive care unit; a critical review. Genes Dis. 2019;6(2):109-19.
7. Marty N, Malavaud S. [Epidemiology of nosocomial infections after cataract surgery and role of the Infection Control Committee in prevention]. Bull Acad Natl Med. 2002;186(3):635-45; discussion 45-8.
8. Tabatabaei SM, Pour FB, Osmani S. Epidemiology of hospital-acquired infections and related anti-microbial resistance patterns in a tertiary-care teaching hospital in Zahedan, Southeast Iran. Int J Infect. 2015;2(4).
9. Haque M, Sartelli M, McKimm J, Abu Bakar M. Health care-associated infections - an overview. Infect Drug Resist. 2018;11:2321-33.
10. Mahmoudi S, Gholampour Noghondar Z, Habibi Nodeh F, Safari H, Abbasi Borogeni P. Identifying and Prioritizing Factors Affecting Patient's Length of Stay in Selected Hospitals Affiliated to Tehran and Iran University of Medical Sciences. J Hosp. 2018;16(4):53-62.
11. Mahon CR, Mahon R. Textbook of diagnostic microbiology: Content Technologies, Inc; 2015.
12. Mythri H, Kashinath K. Nosocomial infections in patients admitted in intensive care unit of a tertiary health center, India. Ann Med Health Sci Res. 2014;4(5):738-41.
13. Behnke M, Aghdassi SJ, Hansen S, Diaz LAP, Gastmeier P, Piening B. The Prevalence of Nosocomial Infection and Antibiotic Use in German Hospitals. Dtsch Arztebl Int. 2017;114(50):851-7.
14. Masters BR. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, (2015) Eds: John E. Bennett, Raphael Dolin, Martin J. Blaser. ISBN: 13-978-1-4557-4801-3, Elsevier Saunders. Springer; 2016.
15. Zahraei SM, Eshrati B, Asi HM, Pezeshki Z. Epidemiology of four main nosocomial infections in Iran during March 2007-March 2008 based on the findings of a routine surveillance system. Arch Iran Med. 2012;15(12).
16. Shaikh JM, Devrajani BR, Shah S, Akhund T, Bibi I. Frequency, pattern and etiology of nosocomial infection in intensive care unit: an experience at a tertiary care hospital. J Ayub Med Coll Abbottabad. 2008;20(4):37-40.
17. Rahimi-Bashar F, Karami P, Khaledi A, Dehghan A, Seifrabie MA, Yaghoobi MH. Evaluation of the Prevalence of Nosocomial Infection in Different Wards of Be’sat Hospital of Hamedan. Avicenna Journal of Clinical Microbiology and Infection. 2018;5(2):31-5.
18. Davoudi AR, Najafi N, Shirazi MH, Ahangarkani F. Frequency of bacterial agents isolated from patients with nosocomial infection in teaching hospitals of Mazandaran University of Medical Sciences in 2012. Caspian J Intern Med. 2014;5(4):227.
19. Behzadnia S, Davoudi A, Rezai MS, Ahangarkani F. Nosocomial infections in pediatric population and antibiotic resistance of the causative organisms in north of iran. Iran Red Crescent Med J. 2014;16(2):e14562.
20. Ghashghaee A, Behzadifar M, Azari S, Farhadi Z, Luigi Bragazzi N, Behzadifar M, et al. Prevalence of nosocomial infections in Iran: A systematic review and meta-analysis. Med J Islam Repub Iran. 2018;32(1):273-82.
21. Dasgupta S, Das S, Chawan NS, Hazra A. Nosocomial infections in the intensive care unit: Incidence, risk factors, outcome and associated pathogens in a public tertiary teaching hospital of Eastern India. Indian J Crit Care Med. 2015;19(1):14-20.
22. Eckenrode S, Bakullari A, Metersky ML, Wang Y, Pandolfi MM, Galusha D, et al. The association between age, sex, and hospital-acquired infection rates: results from the 2009-2011 National Medicare Patient Safety Monitoring System. Infect Control Hosp Epidemiol. 2014;35 Suppl 3:S3-9.
23. Li Y, Ren L, Zou J. Risk Factors and Prevention Strategies of Nosocomial Infection in Geriatric Patients. Can J Infect Dis Med Microbiol. 2019;2019.
24. Babazono A, Kitajima H, Nishimaki S, Nakamura T, Shiga S, Hayakawa M, et al. Risk factors for nosocomial infection in the neonatal intensive care unit by the Japanese Nosocomial Infection Surveillance (JANIS). Acta Med Okayama. 2008;62(4):261-8.
25. Luzzati R, Antozzi L, Bellocco R, Del PB, Mirandola M, Procaccio F, et al. Prevalence of nosocomial infections in Intensive Care Units in Triveneto area, Italy. Minerva anestesiologica. 2001;67(9):647-52.