Showing 14 results for Dadashi
Masoud Dadashi, Maryam Vaezjalali, Fatemeh Fallah, Hossein Goudarzi, Mohammad Javad Nasiri, Parviz Owlia, Ali Hashemi, Davood Darban-Sarokhalil,
Volume 3, Issue 2 (5-2017)
Abstract
Background: Human papillomavirus (HPV) is one of the most common causes of sexually transmitted disease (STD) in humans. HPV is associated with gynecologic malignancy and cervical cancer among women worldwide. In the current study we sought to determine the prevalence rate of HPV in Iranian women identified with cervical infections.
Materials and Methods: Prevalence rate of HPV in Iran was investigated from 2000-2016 using several databases including Medline, Web of Science, Embase, Google Scholar, Iranmedex, and Scientific Information Database. Statistical analysis was performed by Comprehensive Meta-Analysis (V2.2, Biostat) software. Random effects models were used by taking into account the possibility of the heterogeneity between the studies, which was tested through the Cochran’s Q-statistic.
Results: The meta-analyses showed that the prevalence rate of HPV infections was 38.6 % (95% CI, 27.9-50.5) among Iranian women with cervical infections. The further stratified analyses indicated that the prevalence rate of HPV was higher in the studies conducted during the 2000-2008 years.
Conclusion: The results of the present study underscore the need for further enforcement of STD control strategies in Iran. Establishing advanced diagnostic facilities for HPV, vaccination of high risk groups, and continuous monitoring of HPV are recommended for HPV prevention and control.
Volume 3, Issue 3 (Summer 2018)
Abstract
Aims: Despite the high incidence of wrong ways to wear a backpack in students, the relevant musculoskeletal complications, and the effective role of health education in modification of this behavior, there is no standard questionnaire in this regard in Iran. The aim of this study was to assess the psychometric evaluation of a questionnaire on backpack carrying among female high school students.
Instruments & Methods: The questionnaire on how female high school students carry their backpack in Babolsar, Mazandaran province included 31 items for knowledge (12 items), attitude (10 items), and behavior (9 items) derived from evidenced literature. This questionnaire was evaluated in terms of content and face validity and reliability through internal consistency and stability in 2018. The qualitative and quantitative content validity was evaluated by the panel of experts through Content Validity Index (CVI) and Content Validity Ratio (CVR). Qualitative and quantitative face validity was assessed by the students’ views and measuring impact score, respectively. Internal consistency and stability were measured by Cronbach’s alpha and Intraclass Correlation Coefficient, respectively. Data were analyzed by SPSS 21.
Findings: The results of CVI (0.9-1), CVR (0.8-1), and impact score (2.5-3) were acceptable for the whole scale. Qualitative content and face validity was favorable. Cronbach’s alpha coefficients were appropriate for the whole scale (0.77) and of knowledge (0.68), attitude (0.8), and behavior (0.77). The interclass correlation coefficient for the whole questionnaire (0.68) and the domains of knowledge (0.61), attitude (0.71), and behavior (0.72) indicated that the questionnaire was acceptable.
Conclusion: The study showed the validity and reliability of the health questionnaire on carrying backpack among female high school students. However, more researches should be done to verify this questionnaire for measuring knowledge, attitude, and behavior regarding backpack carrying.
Volume 4, Issue 3 (summer 2019)
Abstract
According to the statute of the World Health Organization (WHO), health is considered as an individual and social value, and one of the most obvious human rights and needs. The carriage of heavy schoolbags by children is a concern for all those involved in student health and well-being. Backpacks are the most commonly used type of bag, and overweight backpacks are associated with several health issues, including increased spinal curvature, discomfort, and back and shoulder pain while the majority of students were carrying as much as 30% to 40% of their body weight. In this way posture modifications have been reported when children carry a load that corresponds to more than 10% of their body .
In addition Items carried by students in their daily school bags have been found to include, but are not limited to books, pencil cases, scientific calculators, and sport-specific training clothing, lunch boxes and full water bottles. Even an empty backpack can distort posture and cause pain. There is no way to safely carry weight in a backpack, no matter how light the load, because it disrupts our body mechanics by design .
Volume 5, Issue 4 (Fall 2020)
Abstract
Aims: Back pain is a major public health problem among adolescents and in particular among pupils. This study aimed to evaluate the effectiveness of a back care intervention on spine-related behavior among female students.
Method and Materials: This randomized quasi-experimental study was conducted on female students who were studying in high schools of Babolsar, Iran. Just intervention group received the peer educational program. However, the control group received no intervention. The data were collected by a valid questionnaire regarding backpack carrying . Effective factors in two time points of initial of the study and 6-month follow up were assessed. The data were analyzed by SPSS software version 21 at a significance level of 0.05.
Findings: Totally, 92 students including 46 students in intervention group and 46 students in control group participated in the study. According the findings of the study, mean ± standard deviation of backpack weight before the intervention was (6.14 ± 0.57), ratio of backpack weight to student weight was (0.1 ± 0.01) and backpack carrying duration was (132.6 ± 46.81) which all these variables six months after the intervention reduced to 4.09 ± 0.92; 0.06 ± 0.02 and 93.36 ± 58.06 respectively (P <0.001). The percentage of bilateral backpack carrying in the experimental group increased from 32.6% (n= 15) to 73.9% (n= 34) (P <0.001). However, no significant difference regarding mentioned variables was observed in the control group (P <0.05). The effect size of the intervention was moderate to large (0.4-0.6).
Conclusion: Peer educational interventions could be effective for improving back pack carrying behavior. However, doing more interventional researches in future is recommended.
Volume 6, Issue 1 (winter 2021)
Abstract
Aims: A backpack is considered as one of the most common cases of carrying things to schools. It is argued that improper carrying can lead to musculoskeletal pain in students. Health education through peers can play an important role in promoting proper backpack carrying behaviors. This study aimed to evaluate peer education on how to carry backpacks in female high school students.
Method and Materials: This quasi-Intervention study was conducted on 92 female high school students in Bahnemir, Iran using multi-stage cluster random sampling. The data regarding knowledge, attitude and backpack carrying behavior were collected through a valied questionnaire before and six months after the intervention. Just intervention group received an educational program in four sessions by peers. The data were analyzed by SPSS
version 21 .
Findings: 92 students with a mean age of 13.90 ± 0.71participated in Intervention and control groups (n= 46 in each group). The variables of knowledge, attitude and backpack carrying behavior improved after intervention (respectively (P <0.001).
Conclusion: According to the results of this study, it is suggested to consider these findings in the design, implementation and evaluation of educational interventions to improve carrying behavior of backpacks among this vulnerable target group.
Volume 8, Issue 2 (Spring 2023)
Abstract
Aims: Transportation of patients in hospitals is one of the main reasons for the prevalence of musculoskeletal diseases among health care workers. Considering that the practical action of recognizing and evaluating the studies has been done, therefore the present study has been conducted with the aim of determining the prevalence of musculoskeletal diseases and the determinants affecting the disorders in a systematic manner in Iran.
Method and Materials: In this systematic review, English databases of Web of Science, Scopus, Proquest, PubMed as well as databases Magiran, SID in Iran, and also Google Scholar search engine in the period Jan 1990 to Jan 2020 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement were done. Study process was conducted from 28th September to the end of October. Cochrane (adapted for evaluating interventional studies) and Strengthening the Reporting of Observation Studies in Epidemiology (STROBE) checklists (adapted for evaluating cross-sectional studies) were used to evaluate the quality of the articles. To avoid bias in the study, the data were analyzed by two researchers entirely independently. Any disagreement between the researchers was examined by a third party.
Findings: Out of 93 articles, finally, 10 articles2 (interventional and 8 cross-sectional articles) entered the final list of studies. Thus, the final articles were performed on health system staff (nurse, nurse’s assistance, helper nurse’s assistance and service workers). In all studies, the prevalence of musculoskeletal diseases were highly reported among those responsible for transporting the patient.
Conclusions: Considering the high prevalence of musculoskeletal disorders among the medical staff, the interventions carried out in the field of teaching the correct method of patient transportation in Iran seem insufficient, so that there is a need for better planning and designing more practical interventions. Also, often enough tools and equipment are not available for easy transportation, which should be considered by hospital managers.
Sanaz Mami, Saeedeh Khaleghnezhad, Masoud Mami, Masoud Dadashi, Mehdi Goudarzi, Hossein Ghahremanpour, Bahareh Hajikhani,
Volume 8, Issue 4 (fall 2022)
Abstract
Backgrounds: Helicobacter pylori infections vary in severity and virulence in different populations for various reasons. There are different H. pylori strains with varying degrees of virulence. The genetic diversity of H. pylori strains in gastritis patients in different areas has not been well understood. This study aimed to evaluate the prevalence rate and different genotypes of H. pylori strains in clinical specimens of patients with gastritis in Ilam, Iran.
Materials & Methods: Saliva and gastric biopsy samples were collected from 81 patients (55 males and 26 females in the age range of 20 to 90 years) referring to Ilam medical centers. After DNA extraction, the prevalence of H. pylori as well as vacA, cagA, and ureC genes was evaluated using PCR, and then each vacA-positive sample was further evaluated for m1m2 and s1s2 variants.
Findings: The cagA and vacA genes were found in 27 (71%) and 36 (94.7%) H. pylori-positive samples, respectively. The cagA gene was detected in patients with gastric pain (44.4%) and anorexia (18.51%). Also, the results showed that the vacA s2m2 genotype and m2 allele were present in 32.9% of H. pylori isolates. Moreover, s2m2 and s1m2 genotypes were detected in 42.1 and 26.3% of vacA-positive samples, respectively. The lowest frequency was related to the m1 allele (17.18%).
Conclusion: This study results indicate a plausible relationship between the presence of some genotypes of H. pylori and the progression of gastritis, suggesting these markers as promising biomarkers to predict the disease severity.
Bahareh Hajikhani, Naghmeh Boyaghchi, Samin Mirhosseini, Mehdi Goudarzi, Hossein Goudarzi, Fatemeh Sameni, Masoud Dadashi,
Volume 10, Issue 1 (Winter 2024)
Abstract
Background: A promising strategy in cancer therapy involves the production of fusion proteins, which entail the fusion of two distinct proteins. This study aimed to produce and assess the cytotoxic effects of the Nisin-arginine deiminase (ADI) fusion protein on the SW480 cell lines, a common model for studying colorectal cancer (CRC).
Materials & Methods: The designed Nisin-ADI gene fragment sequence was sent to Biomatik Company for synthesis in pET-28a vectors between SacI and HindIII restriction enzyme sites. Escherichia coli (E. coli) DH5α and BL21 were utilized for cloning and protein expression, respectively. The recombinant fusion protein expression was induced by Isopropyl ß-D-1-thiogalactopyranoside (IPTG) and purified using Ni2+-nitrilotriacetic acid (1) resin affinity chromatography. Sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and Western blotting were conducted to analyze the purified protein. The cytotoxic effect of the purified recombinant fusion protein on SW480 and NIH3T3 cells, as a control, was evaluated using 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay.
Findings: The results of this study showed that the fusion protein had a significant impact on the SW480 cell lines. The Half-maximal inhibitory concentration (IC50) of the fusion protein was 30 µg/mL, indicating that it effectively inhibited the growth of cancer cells. However, the fusion protein did not significantly affect the control group.
Conclusion: This study provides helpful insights into the potential application of recombinant Nisin-ADI fusion proteins as a potential treatment option for colorectal cancer. The potential for selective targeting of cancer cells is promising as normal cells are unaffected by this fusion protein.
Volume 12, Issue 3 (12-2012)
Abstract
This paper presents a gain scheduled autopilot for pitch channel of a flying vehicle. The selected method is based on polynomial fuzzy systems. The method does not involve linearization about operating point. First the polynomial fuzzy model of pitch channel of the flight body is derived. Next, using polynomial fuzzy system methodology the controller is design such that the outputs of the nonlinear plant drive to follow those of a stable reference model. Because of avoiding actuator saturation, some constraints derived that guarantees the amplitude of control signals be less than a specific threshold. It is considered that the controller has a known structure like three-loop autopilot. In other words the three-loop fuzzy polynomial autopilot is design to satisfy stability and performance of the closed loop system over a wide range of parameter variation. Stability and performance conditions derived in terms of sum of square will solve numerically via SOSTOOLS.
Volume 15, Issue 13 (Special Issue 2016)
Abstract
Volume 16, Issue 1 (3-2016)
Abstract
In this paper, tracking control synthesis problem for nonlinear polynomial discrete-time systems are studied. Proposed controller drives the plant such that the state vector of the plant follows those of a stable reference model. The objective is to design a controller such that the energy gains from the exogenous signals that are the reference signal and the state vector of the reference model, to the tracking error to be less or equal to prescribe thresholds. The main difficulty in the problem of designing tracking nonlinear discrete-time control law for the polynomial discrete time systems is that in general this problem may not be formulated as a convex problem. With proper selection of Lyapunov function and based on Lyapunov theory and by using sum of square approach, sufficient conditions for existence of controller are presented in terms of a feasibility SOS programming problem that can be solved using numerical solvers such as SOSTOOLS. Finally, the performance of proposed approach will be shown using the simulation of several examples.
Volume 16, Issue 96 (February 2020)
Abstract
The purpose of this study was to produce red beetroot pulp powder using foam-mat drying technique and to investigate the effect of foam thickness on drying kinetics and physicochemical and microstructural properties of the resulting powder. To prepare foam, ovalbumin as foaming agent at a concentration of 2% (w / v) was added to the red beetroot pulp and was stirred for a specific time and speed. Prepared foam was spread on aluminum plates at thicknesses of 5, 6 and 7 mm and then dried in a hot air cabinet dryer at 50 ºC and constant air velocity of 1 m/s. Results showed that increasing foam thickness from 5 to 7 mm had no significant effect on moisture content and moisture ratio but significantly (p <0.05) reduced the drying rate by about 29.63%. The effective moisture diffusion coefficient was significantly affected by the foam thickness and ranged between 5.550 × 10−9 and 7.388 × 10−9 m2/s. Also, with increasing foam thickness, due to increasing drying time and more denaturation of proteins, an increase in Carr index and Hausner ratio was observed, resulting in a decreasing trend in the flowability of the powders. Bulk and tapped densities of powders were significantly decreased due to the change in moisture content, caused by the increase in foam thickness. Thickness had no significant effect on water solubility index and water absorption index. The microstructure analysis of the produced powders by field emission scanning electron microscope showed that with increasing foam thickness, cracking and surface roughness of powder particles increased. The results of this study and further studies can lead to optimization of red beetroot powder production as a natural food coloring and better preservation of its nutritional and functional properties.
Volume 17, Issue 107 (January 2021)
Abstract
Powdered activated carbon has high adsorption capacity with the remarkable nonpolar surface. The surface forces (van der Waal’s and London) create a stronger attraction between the carbon surface and impurities in comparison to present molecules in dilute molasses. The aim of the study was to adsorb types of impurities such as colorants, turbidity agents, phenolic compounds, anthocyanin and protein of dilute molasses (35% sugar beet dilute molasses) using powdered activated carbon at 4 levels (0.61, 0.78, 1.13, and 1.83 g 100g-1 dilute molasses) at pH 4.5. Further, Freundlich and Longmuir sorption isotherm models were evaluated to predict reduction of impurities. The results of equilibrium isotherms based on the coefficient of determination and adsorption capacity exhibited that the adsorption of impurities such as colorants (R2 = 0.9605 and Kf = 5.0794), phenolic compounds (R2 = 0.7605 and Kf = 0.9755) and protein (R2 = 0.9679 and Kf = 1.9314) didn’t follow from Freundlich model. Turbidity agents and anthocyanin didn’t follow any of the studied models.
Volume 19, Issue 4 (7-2017)
Abstract
Freezing can adversely affect the quality of liquid egg through complex inter-particle interactions of egg micro-particles. The effect of pectin, PG-Alginate (PGA), Arabic Gum, maltodextrin and defrost temperature on the rheological properties, microstructure and color of frozen egg was studied. The fresh sample exhibited a light yellow color with high values of L and positive values of a and b. Freezing resulted in a reduced L value with slight changes in a and b. The additives could enhance the lightness with the closest values of L to that of the fresh sample detected for PGA and pectin. Fresh egg with a low viscosity exhibited near-Newtonian flow behavior. However, the freezing-thawing significantly increased the viscosity. Accordingly, the flow behavior index of the frozen samples was decreased significantly along with a sharp increase in the consistency index, revealing a pseudo-plastic behavior. All frozen samples exhibited higher viscosities than the fresh sample. Fresh samples contained evenly distributed micro-particles ranging from 0.05 to 5.50 mm centering at 1.27 mm. Freezing resulted in aggregated particles with significantly larger sizes. Maltodextrin significantly reduced the particle size. Further reduction was achieved by the addition of pectin, PGA, and Arabic gum. Smallest particle size distributions were achieved at pectin and PGA concentrations of 0.25 and 0.1%, respectively. The results of this study can be employed for the development of new products based on frozen egg with no added sugar or salt, while maintaining the physical and functional properties of the final product.
