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Background: Recently, the use of probiotics in preventing and treating the immune system diseases through changes in blood factors has attracted the attention of researchers. Therefore, the aim of this study was to evaluate the effect of Lactobacillus plantarum and Bifidobacterium B94 on changes of blood factors, influencing the autoimmune system diseases.
Materials and Methods: The rats used in this study were divided into four groups (n=10 each), including control (saline), damage with Ethidium bromide (EB), L. plantarum and Bifidobacterium B94 treatment groups. In damage and treatment groups, a single dose of 3μL EB was directly injected into hippocampus of rats for inducing demyelization. Also, in control group, the same amount of saline was used. Then 2×10⁸ probiotic bacteria were administered by gavage for 28 days. Then serum calcium and cholesterol levels were measured. Data were analyzed by one-way ANOVA and Tukey post-hoc tests (p≤ .05).
Results: The results showed that level of blood serum calcium increased insignificantly in the L. plantarum and Bifidobacterium B94 treatment groups compared to control group.  Also, the level of blood serum cholesterol decreased insignificantly in both treatment groups compared to control group.
Conclusion: Probiotics are used for preventing and treating some of the common autoimmune diseases such as MS. Previous studies showed that probiotics affects some of the blood parameters such as calcium and cholesterol while decrease or increase in these parameters is effective in the improvement of MS.  Although no significant finding has been obtained in some of these studies, they have almost confirmed the recommendation of probiotic consumption.

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Aim: The present study was conducted to validate the international version of the resilience scale (CYRM-28) among adolescent youth students.
Methods: The first original scale was translated into Persian language by two experts. Then an integrated version of the two was translated to the language of the original version again; then it was ensured that the content of the Persian and English versions' was matched. The Persian version scale was filled in by 412 high school students (270 males and 142 females) in Tehran, who were selected as a random cluster. Regarding the clear scale structure to assess the validity, construct validity was used (confirmatory factor analysis) using the LISREL software version 8.8. In addition, scale reliability was examined using the two methods of internal correlation coefficient and test-retest.
Findings: Fit Index confirmed the resilience scales' fit ness in confirmatory factor analysis. In examining the reliability using the internal correlation calculation method (Cranach’s alpha), the value of each sub-scale item, as well as that of total questions was higher than the standard value of 0.7 to confirm the tool's reliability. In examining the reliability using test-retest method, correlation coefficient of each sub-scale in two steps was at an acceptable level and significant.
Conclusion: The present study confirmed the three-factor structure of CYRM-28 scale, including the individual sub-scale's relationship with the primary caregiver and contextual factors in the Persian version of the scale. This study showed that the reliability and validity of the Persian version of CYRM-28 was suitable for measuring the resilience of Iranian children and youth.

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Aim: People receive social support from family, peers, and other social systems. Within this wide spectrum, social networks that support people unofficially involve the group of family and peers. The aim of this study was to determine the relationship between perceived social support and mental health of students in Tehran.
Methods: This descriptive and analytical study was conducted on 227 students in Tehran using two questionnaires including the General Health Questionnaire (GHQ-28) with 28 questions, and the social support inventory with two scales of Perceived Social Support from Family (PSSFA) and Perceived Social Support from Friends (PSSFR). The collected data were analyzed via SPSS18 software using Pearson correlation test.
Findings: The results showed that mental health had significant relationship with the total score of social support (p<0.05, r=0.197). Furthermore, concerning the other subscales, anxiety and sleep disorders (p<0.02, r=0.155) and social functioning (p<0.006, r=0.190) showed significant relationship with mental health. However, there was no significant correlation between PSSFR and mental health.
Conclusion: As proved by the results of this study, when social support is stronger, an individual will have a better mental health status. Moreover, people who experience a higher level of family support have a better mental health status.

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Backgrounds: Infectious diseases are one of the main leading causes of morbidity and mortality worldwide. Therefore, diagnosis and treatment of infectious diseases are very important. Infection affects some blood indices that could be used as diagnostic markers. Therefore, this study aimed to compare blood parameters in four important and prevalent infectious diseases.
Materials & Methods: In this study, 202 out of 892 patients with a final diagnosis of UTI (urinary tract infection), septicemia, pneumonia, or diabetic foot infection were evaluated; they were hospitalized in Rasoul Akram hospital in Iran from August 2017 to February 2018. Patients’ demographic and laboratory data, such as RDW (red cell distribution width), PDW (platelet distribution width), RBC (red blood cell), CRP (C-reactive protein), ESR (erythrocyte sedimentation rate), and, WBC (white blood cells), were evaluated.
Findings: This study results showed that mortality rate in sepsis cases was higher than in other cases (42.1%). Changes in blood parameters such as RDW, PDW, and EDR levels as well as monocyte, basophil, and eosinophil counts were significant among patients with different infectious diseases, while there was no significant difference in terms of changes in some blood parameters, such as WBC, neutrophil, and lymphocyte counts and CRP level between patients with different infectious diseases. For statistical analysis, one-way ANOVA and LSD post hoc tests were used.
Conclusion: According to this study results, it was found that the range of blood parameters varies in different types of infectious diseases. Therefore, the physician could employ routine blood parameters along with other diagnostic factors to more accurately diagnose the type of infection and prescribe more appropriate antibiotics.

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 While the hydrological balance of forest ecosystems has often been studied, quantitative studies on the seasonal variability of rainfall Interception (I) and Canopy Storage Capacity (S) by individual trees are less frequently reported. Hence, the effects of the seasonal variation in I and S by individual Persian oak trees (Quercus brantii var. Persica) in the Zagros forests of Iran were studied over a 1-year period. Annually, I accounted for 84.9 mm (20%) of Gross Rainfall (GR) that significantly differed between the in leaf (47.4 mm or 30% of GR) vs. leafless (37.7 mm or 14% of GR) periods. Negative logarithmic correlations existed between I:GR and GR both for in leaf (r²= 0.808) and leafless (r²= 0.709) periods.An indirect method, outlined by Pereira et al. (2009), estimated S to be 1.56 mm in the in Leaf Period (LP) and decreased considerably to 0.56 mm in the Leafless Period (LLP). The results indicate that while I decreased during the LLP, it still exerts considerable influence on the hydrology of forests. Hence, measurement of I in both the LP and LLP is essential when assessing the water balance on the catchment scale.

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In the current study, the effect of seasonal variation on the type and percentage of phytochemical compounds of Artemisia fragrans Willd. essential oil was investigated. Herbal samples were collected in 4 different seasons and then their essential oils were extracted by the Clevenger type apparatus. In the following, the essential oil compositions of each season was analyzed by GC-MS apparatus. In total, 50 different compounds were identified in four sentential oil. The major components of the essential oil were camphor, thujone, and 1,8-cineole in different seasons. Also, the results showed that monotreptans were the major class of essential oil compounds in September (91.87%), December (90.55%), May (96.32%) and July (95.4%). The highest amount of phenolics (5.49 mg GAE/g) and antioxidant capacity (28.98%) were observed in essential oil of Septebmer.   Antibacterial effects of the different essential oils using paper disc diffusion method were carried out on Escherichia coli, Proteus vulgaris, Klebsiella pneumonia, Staphylococcus aureus, and Bacillus subtilus. Based on the results of the study, gram negative bacteria (E. coli, Proteus vulgaris, and K. pneumonia) were more susceptible to artemisia essential oils in comparison with gram positive bacteria (S. aureus and B. subtilus). The results of this research can be useful in determining the best sampling date of this plant for pharmaceutical and antibacterial uses.

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Demand for the production and consumption of fresh meat has led to the use of various methods to improve the quality characteristics and increase its shelf life. In this study, stinging nettle extract (SNE) in combination with epsilon (ɛ-PL) were used for the production of fresh, functional, and extended shelf life of beef fillets. After drying of stinging nettle leaves under favorable conditions, aqueous extraction was performed at concentrations of 3, 6 and 9% (w/v) of leaves. A solution of ɛ-PL at 0.5% (w/v) concentration was prepared and mixed with 3, 6 and 9% of SNE. Beef fillets (4 treatments) were prepared in 2×2×2 sizes and treated for 1 h at 4 ° C with a ratio of 1 to 1 (meat fillets to SNE). Distillation water was used to treat the control. Finally, beef fillets were packed in polyethylene bags and quality properties were performed at days 1, 3, 6, 9 and 12. During storage, pH, phenolic compounds, redness value (a) and sensory scores decreased significantly (P < 0.05), and in contrast to lipid oxidation, total volatile nitrogen, lightness (L) and yellowness (b) increased significantly (P < 0.05). It was found that the treatment of beef fillets using SNE (6%) in combination with ɛ-PL (0.5%) resulted in a significant reduction (P < 0.05) in the amount of lipid oxidation and total volatile nitrogen compounds of about 50% compared to the control sample. The color and sensory characteristics of processed beef fillets showed that SNE in combination with ɛ-PL could increase the sensory scores of the samples. Based on the results, SNE had synergistic effects with ɛ-PL in reducing lipid oxidation and total volatile nitrogen compounds, therefore it could be used to produce fresh and functional beef.