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The present study is the analysis of the drama “Death of a Salesman” and its interlingual and intersemiotic translations into Persian. The drama has been interlingually translated into Persian and it became the basis for an intersemiotic translation, a tele-theatre. For this reason, the researcher compared the Persian translation with the English text and the tele-theatre to the Persian text to define and analyze the translation of significant ideological concepts in both translations. Then, using critical semiotics theory and extending it to translation criticism, the researcher criticized the tele-theatre from a critical semiotics viewpoint to identify which types of signs have been changed in the tele-theatre and how. Therefore, changes of ideologically significant concepts were analyzed and criticized. The results showed that there were no changes in ideologically significant concepts of the Persian text. But, in the tele-theatre, almost all of these concepts were omitted or completely transformed. In fact, the tele-theatre contains so many censorships in a way that, in some parts, it has lost its cohesion and sometimes even its meanings. In fact, the translator/director has tried to do his best to change the text according to the viewpoints of dominant culture of receiving society. Moreover, maintaining and adding their accepted ideological concepts and omitting or transforming their unaccepted ones, he has tried to represent their values and ideological positions to the receivers. As a result, he has created a text, which lacks cohesion in comparison to the original text and infers meanings, which are sometimes completely opposite to those of the original text.

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The present paper intends to apply the Tense theory of Harald Weinrich to the study of tense in two Persian novels, Boofe Koor and Soveshoon. The findings show that categorization of texts into discussion and narration by Weinrich, could be applied in Persian fiction. Ayande (Future), Haal (Present) and Naqli (Perfect) construct those parts of a text that more tend to have qualities of discussion and discourse. On the other hand, past tenses like Gozashte Sadde (Simple Past), Gozashte Estemrari (Past Progressive) and Gozashte Dour / Ba'eed (Past Perfect) more tend to construct narrative parts of the texts. In addition, each group has its own past, present and future. In discussion system, Naqli plays the role of stating past, Haal is the zero point and states the present and Ayande states the future. On the other hand, in narration system, Gozashte Dour stating past and both Gozashte Sadde and Gozashte Estemrari are zero points and state the present. Moreover, we can say there is not a specific tense in Persian to state the future in this system. Finally, two tenses of Gozshte Sadde and Gozshte Estemarai play a role of foregrounding in narration system. The parts stated by Gozashte Estemrari usually are located on the background of the scene, while the main points of the narration which is stated by Gozashte Sadde are located on the foreground of the scene.

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Background: Escherichia coli (E. coli) strains are among predominant agents causing nosocomial and community acquired infections. The majority of strains encode numerous virulence factors including fimbrial adhesions, secretory proteins and toxins, siderophores, and capsule. This study aimed to investigate the prevalence rate of virulence encoding genes and carbapenem resistance-encoding genes among imipenem-resistant E. coli isolates collected from patients hospitalized in Tehran, Iran.
Materials and Methods: In this cross-sectional study (April 2015-December 2017), 50 non-duplicated carbapenem-resistant E. coli isolates were collected from clinical specimens (stool, urine, blood, and wound) of hospitalized patients in three hospitals in Tehran, Iran. The antibiotic susceptibility profile was determined against 15 antibiotics on Mueller Hinton Agar (MHA) as per CLSI guidelines version 2016. The PCR was used to detect virulence and antibiotic resistance encoding genes.
Results: From a total of 50 carbapenem-resistant E. coli isolates, the highest resistance rate was observed to ceftazidime (100%), tetracycline (88%), amoxicillin (100%), sulfonamide (60%), and the least resistance rate was observed against amikacin (14%), gentamicin (22%), and fosfomycin (0%). The genes mediating resistance were as follows: beta-lactams OXA-48 (8%), IMP (16%), VIM (0%), NDM-1 (0%),  fosA3 (0%), quinolones (qnrA 48%), and colistin mcr-1(0%). Furthermore, the prevalence rates of of fimA, hlyA, cnf1, vat, pic, crl, and papH were 88, 36, 28, 10, 12, 54, and 88%, respectively.
Conclusion: In this study, all imipenem-resistant E. coli isolates were susceptible to fosfomycin, and all were  fosA3 negative. Among carbapenemase genes, IMP and OXA-48 type enzymes associated with higher MIC levels (8 to 32 µg.mL^-1) were detected. In this study, data suggest the role of these carbapenemases in resistance to carbapenems. Furthermore, the presence of multiple drug resistant strains encoding adhesive and secretory virulence factors is a concern for the infections treatment. 

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The current paper arose from the following thought: “What are the methods and techniques used in the translation of Culture-based metaphors?” The data used in this article is the result of a comparative study on the translation of Mathnawi by Reynold Nicholson. We used Harvey 2000 model to advance the research. In accordance with the needs of the study, metaphoric significance is presented. Six different types of significations are recognized here; than a sextet significance pattern, is presented, which might be used for any two languages being source and target for translation. As the final outcome of the research, different suggestions for these different signification types have been presented, which are based on the nature of the metaphors. Having these suggestions in hand, translators have a model to follow, so that they can overcome the translatability problems they may face in translation of metaphorical expressions. In the other words, applying this newly-born significance into translation practice and, finally, presenting a model for the translation of culture-based items are  two main achievements of the research.  

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Aims: Many infectious diseases had traditionally been cured with herbal medicines. Antimicrobial agents are often produced synthetically to increase the food durability and quality. The purpose of this study was to determine the antimicrobial properties of the aqueous and alcoholic extracts of Allium schoenoprasum.
Materials & Methods: In this experimental study, after preparation Allium schoenoprasum samples, aqueous and alcoholic extracts were prepared and their minimum inhibitory concentration (MIC) was determined against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Vibrio cholerae by micro broth dilution method. Erythromycin was used as the control.
Findings: The MIC of alcoholic and aqueous extracts of A. schoenoprasum was 16-256 and 32->256µg/ml, respectively and MBC of them were 32-256 and 64->256ug/ml, respectively. The A. schoenoprasum exhibited higher activity against S. aureus and B. cereus strains.
Conclusion: The extracts of A. schoenoprasum have antimicrobial effect on S. aureus, B. cereus, E. coli and V. cholerae strains in micro broth dilution method.

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Aims: Infections by extended-spectrum beta-lactamase (ESBL) and carbapenemase-producing Enterobacteriaceae (CPE) are increasing problems in pediatrics and are usually associated with higher hospital costs and mortality rates. The aims of this study were the statistical investigation of the worldwide prevalence and risk factors of ESBL and CPE family members among pediatric population.
Instruments and Methods: From October 1, 1995 to July 27, 2017, some keywords including “ESBLs”, “carbapenemase”, “pediatrics”, “children”, and “risk factor” were searched in the searching databases such as Google Scholar, Embase, Scopus, PubMed, and Web of Science among original research articles. The univariate and multivariate analysis of the collected data was performed by Graph Pad Prism 6.1 software.
Findings: The mean percentage of ESBL production was 20.23±22.31 and the mean percentage of CPE was 1.81±2.77. E. coli (n=991) and K. pneumonia (n=627) were the predominant ESBL-producers. Nephrology (n=5005) and NICU (n=1805) were predominant hospital wards. ESBL-PE had significantly higher prevalence in the infants unit (OR=0.9832, 95% CI=12.271-19.519; p<0.001). Moreover, ICU ward was a significant and independent risk factor for CPE acquisition (OR=0.849, 95% CI=2.211-5.415; p=0.0035). ESBL-PE and CPE were significantly isolated from blood samples (OR=0.9276, 95% CI=1.508-2.433, p<0.0001) and fecal specimens (OR=0.968, 95% CI=2.829-5.133, p<0.0001), respectively.
Conclusion: Most of risk factors between ESBL-PE and CPE are similar including previous hospitalization and prolonged use of antibiotics, cephalosporins, and previous colonization. Other possible potential risk factors that should be considered include presence of catheters and travel history. Detection of risk factors provides useful information for formulation of infection control policy.

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According to the usual definitions of ambiguity and amphiboly in rhetorics, the origin of amphiboly and ambiguity lies in polysemic words and position and intention of the speaker are the distinctive factors in the respect. Questioning this distinction, co-text is introduced as the criterion of differentiating amphiboly from ambiguity and as a result of such discussion a definition is formed which is the base of the arguments of this paper. The concept of multiple signification is considered equal to the application of polysemic words and the stability of semantic ambiguity resulting from multiple signification, is considered as the required condition of considering a case as amphiboly. In search of the possibility of amphiboly in theater de-contextualization of situational contexts, possibility of negation of various signifieds in any of semiotic systems in theater and impossibility of formation of various signifieds in the mind are considered to be the limiting factors.

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Three main elements of recipient, enunciator and utterance are involved in any enunciation. Studies performed on apostrophe by the Western scholars and Iranians show that how this rhetorical device targets the reciepient while Arab rhetoricians discuss that apostrophe affects both the enunciator and the utterance. The Holy Quran is the most important text in Arabic, and Arab rhetoricians refer to Quranic verses as the main evidence of their theory on apostrophe. In this article, while studying the different types of apostrophe in Quran, we will show how it affects all three elements of enunciation.

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The current research, taking into account three standards of Beaugrande & Dressler’s textual-cognitive model i.e. cohesion, coherence, intertextuality, explains the four-fold stages of textual perception in Sohrab Sepehrie's poetic collection Zendegi-ye Khwabhâ (Dreams’ Life). The aim of the study is to find a new analytical method of the contemporary poetry that is identified through the text hence; it is a collection of identical and mental processes that gradually ring forth the method of understanding and stages of perception to readers. Based on the above model, this study elaborates on a quadric procedure, consisting of parsing, concept recovery, idea recovery and plan recovery for perceiving Sepehrie’s poetry. Here, “parsing” is achieved through collocation; “concept recovery”, through finding the schema; “idea recovery” through taking a sequence of actions and looking for background knowledge and intertextuality; and finally the “plan recovery” through attachment. In other words, a receiver arrives at sequence of actions following collocations that fills the gap in the text and discovers the poet’s schema through sharing his/her background information with instances of intertextuality. Sepehrie succeeded in expressing his metaphysical experiences in a compact way through repeating and describing a chain schema via appealing to surrealism and mysticism as elements of intertextuality.

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The present research examines the concept of love in two separate and distinct spheres. On the one hand, love is considered as a transcendental experience and concept that is static and related to a meta-human truth. This type of reading of love is mainly initiated and developed through Plato’s writings. On the other, there is a view that considers love (even in its Platonic sense) a humane, cultural and more importantly “textual” phenomenon. In other words, love can only be understood, multiplied and experienced within language (or as Jacques Lacan calls, “symbolic order”). In this paper, I have studied these two views in relation to the collection of short stories entitled, Love on the Sidewalk, written by the contemporary Iranian writer, Mostafa Mastour. In order to do this, I have first studied the concept of ‘absence’ in love and how the experience of love always depends on the absence of the lover or the beloved. I then argue that love, in these stories, is a ‘sign’ that is constructed and signified with a system of signs. And finally I illustrate how the characters in these stories fall in love and understand love through “narratives of love”. All this would give love a plural and narrative significance. Love is therefore a sign that is always in the process of being constructed.

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Metaphor is one of the most important issues in Cognitive Linguistics. This paper tests the contemporary theory of metaphor, particularly, the conceptual metaphor of “Time as Space Metaphor” in children fiction books. The research method is descriptive-analytic and data gathering has been library based. Sixty children story books have been chosen by the researchers from three different age groups: 5-7 year-olds; 7-9 year-olds; and 9-11year-old children. Then, the sentences which have the conceptual metaphor of “The Time as Space Metaphor” were chosen. This study concludes that: (1) Persian native children learn the concept of time which is spatial not only by the linear movement in the space but also by movement in different dimension; (2) Persian native children learn the concept of time which is spatial by the use of ontological metaphors; and (3) the contemporary theory of metaphor is a useful means of teaching ‘time’ to Persian native children.

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در این مقاله اثر ضد رگ‌ زایی داروی آرتیمیزینین برای مقابله با رشد تومور سرطانی مورد بررسی قرار گرفته است.به این منظور از رویکرد مدلسازی استفاده شده است. ابتدا یکی از مدل‌ های موجود در ادبیات برای انطباق با نتایج تجربی، بهبود داده شده و سپس پارامتر های آن با استفاده از روش بیشترین شیب بر مبنای داده‌ های آزمایشگاهی جمع‌ آوری شده از موش‌ های آزمایشگاهی استخراج شده است. سپس بر مبنای مدل استخراج شده، روش پایداری لیاپانوف برای طراحی برنامه دارو دهی مد نظر قرار گرفته و یک برنامه دارو دهی برای درمان و کنترل رشد تومور سرطانی ارائه گردیده است. با استفاده از شبیه‌ سازی های رایانه ای نشان داده شده است که برنامه دارو دهی ارائه شده مناسب بوده و می‌ تواند منجر به ایجاد بهبود در روند درمان و کنترل رشد تومور سرطانی گردد. در طراحی برنامه دارو دهی مقدار سمیت داروی آرتیمیزینین نیز لحاظ شده است.

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In this study, we attempt to investigate the representation of sexuality in the images of English language teaching books (Four Corners (2) – American English File (2) – Interchange (2)) based on visual - social semiotics according to Halliday’s Functional linguistics and clearly followed by Kress and Van Leeuwen 2006 (1996).  Creating text, as an example image, is a discoursal and as a result a social action. This social action on textbooks which have been written for non-English language learners works at higher level. It works in intercultural level. As a result, there is always a constant problem: Is it possible that the central culture (English language society) creates discourse via the texts of the textbooks in which non-English speakers are considered strangers and they themselves are considered natural and familiar? This research via investigating images, texts , verbal titles and the margin of those images searches how English language teaching books portray English culture as evident, natural and inevitable and others as foreigners who only lose their alterity if they are attracted by this culture. The main goal of this research is to analyze English language teaching books and investigate their different discoursal, social and cultural outputs .Also this research tries to investigate the role of images in intercultural discoursal context. Cultural differences and their reflection in English language teaching textbooks with ideological outputs of images and modality in the images of textbooks are other marginal goals of this research.  

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This research tries to study the migration Persian literature novels and analyzes the challenge of identity-makers elements in the motherland and host country in inter-discourse migration spaces. The aim of this study is to answer this main question: What challenges would build the motherland identity-makers elements relocate human subject from native Semiosphere to the host Semiosphere?
The article uses the theoretical foundations of cultural studies and the theory of Semiosphere of Juri Lotman to answer this question. This article assumes that identity-makers elements lose an important part of their power and influence after withdrawal from the sphere of their Semiosphere.
 These identical signs in the host territory, since they lose the supporting powers and because of the differences and conflicts they have with identical signs of host, may be sent to margin. Or they are inflicted with change in their value. And as the result, the human subject gets many identity-makers challenges. These challenges vary from liminal identity to identity crisis and identity less.
 
 

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This paper examines the interaction between the visual and the verbal modes, that is, the multimodality of transferring the meaning in Persian visual poetry in terms of cognitive base of different types of integrations which occur in the brain after different sensory channels transferring the visual and verbal data. Although contemporary poetry is multimodal, the visual poetry is considered a type of poetry that has both the verbal and the visual as the dominant, mixed modes that tend to construct the poetic meaning. Different arrangement of words and images, which has a neurological ground, requires different kinds of cognitive processing and will therefore induce different feelings, impressions, and connotations. Consequently, the general meaning of a multimodal text goes beyond that of the combination of the two modes.
Drawing on cognitive semiotics, this paper demonstrates how the multimodal poem is conceptualized through embodied experience. Furthermore, it shows how various types of visual/verbal synthetization in a poetry text are differed by a number of distinctive features. Moreover, it is shown how the meaning-making process and the resulting affection become possible in each type of visual poetry. Through modifying Aarhus’s model (2005, 2012), itself based on Fauconnier and Turner’s conceptual blending theory, this research puts forward twelve different types of interaction between the verbal and visual modes, which, in this paper, are mentioned just the three super basic classified categories due to the limitation of the journal’s space. In fact, the three super categories are:
It is about the general relations among the two or more modes or media. In this kind of relation, each mode/medium comprises separable and individually coherent texts in different mode/media to improve the meaning space at the end.  It is divided into two sub-groups, which are Mode-adjacency and Multimodality.
It is a kind of transformations from one medium to another. An inter-medial text could be divided into Duplicating and Iconicity (Image iconicity, Relational diagram iconicity and Structural diagram iconicity). Duplicating could not presents an indissoluble connection of diverse modes as a fusion of different modal processes, while in the second one (Iconicity), the verbal and visual modes are fused together to represent the similarity or adjacency. The Duplicating could also be based on similarity or contiguity as well, that is the whole or a part of the text could be duplicated due to similarity of the verbal mode to visual mode or the contiguity of both together.
The third and the last type of relation between verbal and visual modes is mix-modal text, which is the combination of modes in a way that the complex signs in different modes would not be coherent or self-sufficient outside of that context. It is divided into four groups which are called in this research Counter-iconicity (Counter iconicity of mis-matching and Paradox-counter iconicity), Mode-situational inclusion, Mode-overlapping and complementary relation. Cognitively, these three basic types are processed respectively as following: bottom-up, top-down and integrated processing. Furthermore, these types are based on the structure of human brain and the functions of neurological cells, to study multimodal, especially visual poetry. Since both brain and literature contain similar patterns, it is inferred that each type of verbal-visual interaction that is constructed through a particular cognitive process will necessarily form specific emotions and impressions.
 
 

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Nowadays different discourses compete to have the most influence on the people’s minds to change into the power discourse. The present article shows how power and counter- power metaphors are made and used. To this end,  in a corpus type of study, 600 articles of two parties - conservatives (Osool- garayan) and reformists  ( Eslah –talaban) - during their counter- power and power period were chosen. The metaphors were extracted and analyzed using a critical- cognitive approach in a descriptive – analytic method, according to Chartris – Black 2004 and Hart and Lukes (2007). The results show that the hegemonic discourse uses media to manipulate the personal and social sources of knowledge as well as choosing metaphors and forming the mental concepts and giving the related information. In this way they reform the cognition and experiential latitudes. They reconstruct new metaphors using ideology, culture and history to legitimate the counter- power discourse and delegitimize the power discourse in order to convince. Media repeat the desired metaphors and construct people’s concepts and finally beliefs. If a discourse has legitimacy, the counter- power discourse uses its words and metaphors. According to the findings of the research the metaphorical schemas of some concepts such as government, election, power etc. are used completely different in these two discourses and delegitimize each other.
 

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Backgrounds: In developing countries like Nigeria, screening of Zika virus (ZIKV) infection in pregnant women remains limited due to a lack of diagnostic facilities and non-specific symptoms, leading to potential misdiagnosis of the disease as other febrile illnesses such as malaria or typhoid.
Materials & Methods: To address this issue, this study aimed to investigate the prevalence of anti-ZIKV IgM antibodies in pregnant women using enzyme-linked immunoassay. Additionally, the quantitative reverse transcription polymerase chain reaction (RT-qPCR) assay targeted a specific region of the membrane protein (prM) gene to detect Zika virus presence in the collected serum samples. For a period of four months from December 2021 to March 2022, a total of 360 serum samples were collected from pregnant women attending antenatal care units in two tertiary hospitals located in different regions of Nigeria.
Findings: The results of this study revealed a prevalence of 17.2% (62 samples) for anti-ZIKV IgM antibodies among pregnant women. Further analysis using the RT-qPCR method detected Zika virus (prM gene) in 1.9% (7/62) of the serum samples. In addition to these virological results, the statistical analysis of sociodemographic data, clinical characteristics, and risk factors for ZIKV infection demonstrated a significant correlation between seropositivity and various factors including ethnicity, residence, occupation, and history of arboviral diseases (p< .005).
Conclusion: Given the potential consequences of ZIKV infection in pregnant women, early diagnosis and intervention could improve maternal outcomes and prevent fetal abnormalities.

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When a text is comprehended in a familiar context and enjoys a coherent whole, it is called a discourse. Reading a discourse is owed to linguistic knowledge and non-linguistic cognition. As a narrative, an autobiography has its textual world. Its reality is a result of the method used for linguistic coding. Through the linguistic relativity on the part of the author, the self and the world are actively constructed. Through an analysis of linguistic domain in autobiography, for denotative meaning and connotative meanings, the author’s worldview is known. The subject in autobiography is moving from one experience to another. It is placed on a continuum of language, adopting multiple positions arisen from connotative utterances. Performance of this self has become a postmodern norm. We should ask about the relation between language and reality in autobiography, and about aspects of cultural identity of the self-represented. This article attempts to say that in our reading of a postmodern subject in the center of autobiography, in view of language as a medium for expression, and meta-language as a language to explain the language used to represent the self, how the multiple “self” & “others” arisen from such texts could be realized in language and participate in various discourses.
 

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This essay denotes the context for observation of cultural behavior of the sixth decade according to cultural formation and discourse analysis of this decade, those groups into the same historical era who have the same experience from the particular social occurrence - the WAR and holy defense. In this analysis of generation dependencies, theories, judgments and common values are studied about stable phenomenon, common meanings which is in the field of experience from the hidden generation, and transfer in this decade narrative stories. In this present essay to understand the interrelation of generations for narrative authors, we assist two terms: 1. the qualification that bring social sources and areas for this changes, and 2- the qualifications that come to form the content and ideological setting, and shows that traditional revolutionary ideological discourse creates a vast array of new ideas through the production processes, selection, and institutionalization which in significant way deployed the ideology of official and cultural deep-seated institutions. This discourse is a function of cultural formulations of sixth decade that is created in order to the crisis in moral system, resources mobilization, and the formation of chains of interaction among the cultural elites. In this cultural context, narrative authors advocated dominant discourse with their new ideas and provoked the answers of the other actors in the present social environment. The Cycle of “idea- answer- idea” is one of the methods and mechanisms of action that acts through the chains of action with formation of repeated dominant discourse. In this way, social experiences of the authors in this period, are as same as the ideological elements with positive and negative elements were recorded and written.