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Showing 2 results for Geriatric
Christopher Paul Clement Jenil Dhas, Yoganathan Chidambaram, Srinivasan Kesavan, Kalaivanee Balasubramaniam, Sujith Kumar Sivaraj, Saravanan Thangavelu,
Volume 10, Issue 1 (2-2024)
Abstract
Background: This study aimed to evaluate serum levels of interleukin-6 (IL-6) and D-dimer and their association with morbidity and mortality in elderly coronavirus disease-19 (COVID-19) patients and to assess their clinical outcomes.
Materials & Methods: This retrospective observational study was conducted on elderly COVID-19 patients (≥60 years) diagnosed via reverse transcription-polymerase chain reaction (RT-PCR) or radiological tests in a South Indian tertiary care hospital. Data encompassed demographics, comorbidities, symptoms, IL-6 and D-dimer levels, oxygen (O2) requirement, duration of hospital stay, and outcomes. Statistical analysis involved Chi-square test. A p-value of < .05 was considered statistically significant.
Findings: Among 1448 screened patients, 1380 patients with a mean age of 68.85±6.985 years were included in this study, of whom 61.67% were male. The mortality rate was 12.1% in males and 11% in females. Fever, cough, hypertension, and diabetes were common in most of the patients. The mean D-dimer and IL-6 levels were 2.687±5.189 mg/L fibrinogen equivalent units (FEU) and 95.72±335.62 pg/mL, respectively. Elevated D-dimer (71%) and IL-6 (87.7%) levels were significantly associated with oxygen requirement, morbidity, and mortality (p= .000). Sub-group analysis revealed a significant association between D-dimer and IL-6 levels and O2 requirement and mortality in diabetic and hypertensive patients (p= .000).
Conclusion: Serum IL-6 and D-dimer levels are significantly associated with morbidity and mortality in elderly COVID-19 patients. Elevated levels of these biomarkers also influence O2 requirement and mortality in patients with comorbidities, suggesting their potential use in risk stratification and management strategies for this vulnerable population.
Volume 10, Issue 3 (7-2022)
Abstract
Aims: The present study aimed to determine the oral health-related quality of life in the retired elderly population.
Material & Methods: A descriptive-analytical cross-sectional study was conducted on 196 elderly members of retirement centers using convenient sampling in Rasht city, Iran. Data collection included oral examinations and structured interviews. The geriatric oral health assessment index was used to measure oral health-related quality of life. Moreover, information on sociodemographic characteristics, use of dental services, and subjective health measures were collected. The independent t-test and ANOVA were used for statistical analysis in SPSS 21.
Findings: The mean GOHAI score was 47.5±6.3 (range 26-59). The mean psychosocial domain score was significantly lower than others (p<0.001). Participants with complete dentures and those with more than 20 teeth showed the highest, and those with partial dentures had the lowest quality of life. Xerostomia was the most prevalent oral condition (29.1%).
Conclusion: The findings indicated the retired elderly who were members of the retirement center had a moderate level of oral health-related quality of life. The obtained data on oral health-related quality of life in the elderly can help the decision-makers plan oral health programs for the elderly.
