Volume 9, Issue 4 (2023)
IEM 2023, 9(4): 311-321 |
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Tarkhan F, Aaliehpour A, Sepahvand A. Automated Blood Cell Counting in Candidaemia: A Comparative Study of Sysmex-X Series 500 and KX-21 Counters. IEM 2023; 9 (4) :311-321
URL: http://iem.modares.ac.ir/article-4-70877-en.html
URL: http://iem.modares.ac.ir/article-4-70877-en.html
1- Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
2- Department of pathology Sciences, Lorestan University of Medical Sciences, Khorramabad, Iran
3- Razi Herbal Medicines Research Center, Department of Medical Parasitology and Mycology, School of Medicine Lorestan University of Medical Sciences, Khorramabad, Iran , fungimed44@yahoo.com
2- Department of pathology Sciences, Lorestan University of Medical Sciences, Khorramabad, Iran
3- Razi Herbal Medicines Research Center, Department of Medical Parasitology and Mycology, School of Medicine Lorestan University of Medical Sciences, Khorramabad, Iran , fungimed44@yahoo.com
Abstract: (333 Views)
Aims: Hidden fungal infections may lead to errors in blood cell counts and inappropriate treatment selection with serious consequences in many patients. This study aimed to evaluate the results of two automated blood cell counters Sysmex-X 500 and KX-21 in samples containing Candida albicans and Candida glabrata.
Materials & Methods: In this study, 144 blood samples of O- blood type were examined in the presence and absence of C. glabrata and C. albicans fungi at different concentrations by two automated blood cell counters Sysmex-X 500 and KX-21 in Lorestan University of Medical Sciences in 2017. Fungal samples were prepared at a concentration of 0.5 McFarland, equally added to the blood samples, and read by Sysmex-X 500 and KX-21.
Findings: The average number of erythrocytes, leukocytes, and platelets read by Sysmex-X 500 and KX-21 devices increased in the presence of both fungal samples compared to the primary samples. In addition, the number of lymphocytes, neutrophils, and monocytes read by Sysmex-X 500 and KX-21 devices in the presence of fungal samples was significantly higher compared to the primary samples (p< .05). The increase in mean blood cell counts in the presence of both fungal samples was significantly higher in X 500 than in KX-21 (p< .05).
Conclusion: This study results showed that among these two devices, the Sysmex-X Series 500 device showed less variation compared to the actual values of blood cells. The use of this device seems to reduce measurement error in blood cell counting.
Materials & Methods: In this study, 144 blood samples of O- blood type were examined in the presence and absence of C. glabrata and C. albicans fungi at different concentrations by two automated blood cell counters Sysmex-X 500 and KX-21 in Lorestan University of Medical Sciences in 2017. Fungal samples were prepared at a concentration of 0.5 McFarland, equally added to the blood samples, and read by Sysmex-X 500 and KX-21.
Findings: The average number of erythrocytes, leukocytes, and platelets read by Sysmex-X 500 and KX-21 devices increased in the presence of both fungal samples compared to the primary samples. In addition, the number of lymphocytes, neutrophils, and monocytes read by Sysmex-X 500 and KX-21 devices in the presence of fungal samples was significantly higher compared to the primary samples (p< .05). The increase in mean blood cell counts in the presence of both fungal samples was significantly higher in X 500 than in KX-21 (p< .05).
Conclusion: This study results showed that among these two devices, the Sysmex-X Series 500 device showed less variation compared to the actual values of blood cells. The use of this device seems to reduce measurement error in blood cell counting.
Article Type: Original Research |
Subject:
Mycology
Received: 2023/08/2 | Accepted: 2024/02/5 | Published: 2024/02/5
Received: 2023/08/2 | Accepted: 2024/02/5 | Published: 2024/02/5
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