Volume 9, Issue 1 (2023)                   IEM 2023, 9(1): 0-0 | Back to browse issues page

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Alrashdi D Y B A, Hossain D M A. Review on Phytochemicals and Pharmacological Activities of Syzygium aromaticum. IEM 2023; 9 (1)
URL: http://iem.modares.ac.ir/article-4-62873-en.html
1- School of Pharmacy, College of Pharmacy and Nursing, University of Nizwa, P. O. Box 33, Postal Code 616, Nizwa, Sultanate of Oman , alrashidi-un@unizwa.edu.om
2- School of Pharmacy, College of Pharmacy and Nursing, University of Nizwa, P. O. Box 33, Postal Code 616, Nizwa, Sultanate of Oman
Abstract:   (160 Views)
Aims: Syzygium aromaticum L (S. aromaticum, clove) is a plant species that belongs to the Myrtaceae family. It is cultivated in many African and Asian countries. Folk medicine practitioners use different parts of the selected plant to treat GI problems, diarrhea, dental pain, ulcer, and other chronic diseases. The experimental data from the previous findings on phytochemicals and pharmacological activities of the target plant are scattered or not systematic. Therefore, the aim of this present review is to explore the available data on the phytochemicals and pharmacological activities of various polarity extracts and the essential oil of S. aromaticum.
Materials & Methods: However, the literature showed that only a few studies had been conducted on the selected plant species; consequently, there is not enough documented information about the bioactive phytochemicals and pharmacological activities of the selected plant species.
Findings: Most of the previous studies described significant bioactive phytochemicals contents: namely eugenol (49.7%), caryophyllene (18.9%), benzene,1-ethyl-3-nitro (11.1%) along with minor phytochemicals including carotenoids, gallic acid, flavonoids, oxalic acid, tannins, amino acids, fatty acids, cyanidin glycoside. Sugars, coumarins, oleanolic acid, saponins, glycosides, and lipids are also present in the species. The methanol extract of the plant and its derived different polarity fractions have shown significant antimicrobial, antioxidant, anti-allergic, antidiabetic, antihypertensive, anti-inflammatory, antifungal, and anticancer activities. Furthermore, the extracts also have chemoprotective and hepatoprotective properties.
Conclusion: The current review will provide comprehensive data on botanical aspects, phytochemicals and pharmacological activities for future researchers to explore the traditional and medicinal uses as well as the production of commercial drugs from S. aromaticum.
Article Type: Analytic Review | Subject: Virology
Received: 2022/07/13 | Accepted: 2022/12/2 | Published: 2023/03/10

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